The Mediator Release Test (MRT) is an advanced blood test designed to identify food and chemical sensitivities that may be driving chronic inflammation in the body. Unlike traditional allergy tests that detect IgE-mediated reactions, MRT measures the release of inflammatory mediators—such as histamine, prostaglandins, and cytokines—from white blood cells in response to specific substances. This test is particularly useful for uncovering non-IgE sensitivities that contribute to a wide range of symptoms, including headaches, fatigue, joint pain, IBS, and conditions like fibromyalgia. Because fibromyalgia is often associated with chronic inflammation and heightened nervous system sensitivity, identifying and removing dietary triggers through MRT-guided nutrition can play a key role in reducing symptom severity and improving overall well-being. MRT is commonly used in functional and integrative medicine and is typically paired with a customized elimination diet for long-term symptom relief.
Chronic inflammation is a key contributor to many disease states, often worsening their progression and intensity. Conditions such as fibromyalgia, rheumatoid arthritis, inflammatory bowel disease (IBD), migraines, eczema, psoriasis, and even metabolic disorders like type 2 diabetes and cardiovascular disease are all influenced by persistent inflammatory activity. In many cases, the immune system reacts to harmless substances—such as certain foods or food additives—creating a cycle of inflammation that fuels ongoing discomfort and dysfunction. By identifying these hidden triggers with tools like MRT, it becomes possible to reduce systemic inflammation, ease symptoms, and enhance the effectiveness of other treatments. For individuals struggling with chronic conditions, this personalized, food-first approach offers a powerful path toward healing and improved quality of life.